Maine Beer Company of Freeport, WEX of Portland, Sargent Corporation of Orono and Panolam Surface Systems of Auburn received awards at the Blaine House.
Janet Mills said the companies embody the best of what the state has to offer.
The annual awards, which have been handed out since 1991, honored companies this year in the categories of innovation, rural revitalization and heritage industries.
A customized collection of grant news from foundations and the federal government from around the Web.
First Enterprise Business Agency (FEBA), a Nottingham-based business support organization, is a contender for two categories at the first Citi Microentrepreneurship Awards to be held this coming February.